Phentolamine in heart block.

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Phentolamine in Heart

5. Dushane JW, Kirklin JW: Late results of the repair of ventricular septal defect on pulmonary vascular disease. In Advances in Cardiovascular Surgery, edited by Kirklin JW: New York, Grune and Stratton, 1973, p 9 6. Jarmakani MM, Graham TP Jr, Canent RV Jr., Spach MS, Capp MP: Effect of site of shunt on left heart volume characteristics in children with ventricular septal defect and patent du...

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Hyperkalemia-induced complete heart block

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Phentolamine block of KATP channels is mediated by Kir6.2.

The ATP-sensitive K+-channel (KATP channel) plays a key role in insulin secretion from pancreatic beta cells. It is closed both by glucose metabolism and the sulfonylurea drugs that are used in the treatment of noninsulin-dependent diabetes mellitus, thereby initiating a membrane depolarization that activates voltage-dependent Ca2+ entry and insulin release. The beta cell KATP channel is a comp...

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Metabolic forearm vasodilation is enhanced following Bier block with phentolamine.

The extent to which sympathetic nerve activity restrains metabolic vasodilation in skeletal muscle remains unclear. We determined forearm blood flow (FBF; ultrasound/Doppler) and vascular conductance (FVC) responses to 10 min of ischemia [reactive hyperemic blood flow (RHBF)] and 10 min of systemic hypoxia (inspired O(2) fraction = 0.1) before and after regional sympathetic blockade with the al...

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Paroxysmal Heart Block in Bundle Branch Block.

When a patient is suspected of having Stokes-Adams disease the electrocardiogram is of critical importance, particularly in respect of the auriculo-ventricular (A-V) conduction time. Should this not be prolonged, the possibility of paroxysmal heart block remains, although the diagnosis of Stokes-Adams disease is uncertain without some degree of heart block recorded graphically. It is not known ...

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ژورنال

عنوان ژورنال: BMJ

سال: 1970

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.4.5730.307-b